Itemoids

Columbia University

What to Read If You’re Angry About the Election

The Atlantic

www.theatlantic.com › books › archive › 2024 › 11 › election-anger-rage-despair-book-recommendations › 680709

A close friend—someone whom I’ve always thought of as an optimist—recently shared his theory that, no matter what time you’re living in, it’s generally a bad one. In each era, he posited, quality of life improves in some ways and depreciates in others; the overall quotient of suffering in the world stays the same.

Whether this is nihilistic or comforting depends on your worldview. For instance, plenty of Americans are currently celebrating the outcome of the recent presidential election; many are indifferent to national politics; many others are overwhelmed with anger and despair over it. Looking at the bigger picture, I think the upsides of contemporary life—antibiotics, LGBTQ acceptance, transcontinental FaceTime—outweigh the horrors more often than not. I’ll also concede that this decade comes with a continuous drip of bad news about ghastly acts of violence, erosion of human rights, and climate disaster. Perhaps unsurprisingly, a 2023 Gallup poll found that rates of depression in the United States have hit a record high.

What can people turn to when the itch to burn everything down, or to surrender to hopelessness, feels barely suppressible? I agree with the novelist Kaitlyn Greenidge that there is power in “naming reality”in telling, and writing, the truth about what’s happening around us. For those who are despondent about Donald Trump’s victory and feel unable to make a difference, reading might be a place to start. This doesn’t necessitate cracking open textbooks or dense political tracts: All kinds of books can provide solace, and the past few decades have given us no shortage of clear-eyed works of fiction, memoir, history, and poetry about how to survive and organize in—and ultimately improve—a broken world.

Reading isn’t a panacea. It’s a place to begin and return to: a road map for where to go from here, regardless of where “here” is. Granted, I am perhaps more comfortable than the average person with imperfect solutions. As a clinical pharmacist, I can’t cure diabetes, for example, but I can help control it, make the medications more affordable sometimes, and agitate for a better health-care system. Similarly, these seven books aren’t a cure for rage and despair. Think of them instead as a prescription.

Which Side Are You On, by Ryan Lee Wong

Wong’s novel opens with a mother picking up her son from the airport in a Toyota Prius, her hands clutching the wheel in a death grip. Wry, funny moments like this one animate Wong’s book about the dilemma of trying to correct systemic problems with individual solutions. It’s 2016, and spurred by the real-life police shooting of Akai Gurley, 21-year-old Reed is considering dropping out of Columbia University to dedicate himself to the Black Lives Matter movement. Reed wants nothing more than to usher in a revolution, but unfortunately, he’s a lot better at spouting leftist talking points than at connecting with other people. Like many children, Reed believes that his family is problematic and out of touch. His parents, one a co-leader in the 1980s of South Central’s Black-Korean Coalition, the other a union organizer, push back on his self-righteous idealism. During a brief trip home to see his dying grandmother, Reed wrestles with thorny questions about what makes a good activist and person. Later, in the Prius, Reed’s mother teaches him about the Korean concept of hwabyung, or “burning sickness”—an intense, suppressed rage that will destroy him if he’s not careful—and Reed learns what he really needs: not sound bites but true connection. Wong’s enthralling novel is a reminder that every fight for justice is, at heart, a fight for one another.

Hope in the Dark: Untold Histories, Wild Possibilities, by Rebecca Solnit

Solnit’s short manifesto about the revolutionary power of hope is a rallying cry against defeatism. She begins by critiquing the progressive tendency to harp on the bleakness of societal conditions, insisting that despair keeps oppressive systems afloat. Hope and joy, by contrast, are essential elements of political change, and celebrating wins is a worthy act of defiance against those who would prefer that the average person feel powerless. Originally published in 2004 after the U.S. invasion of Iraq, and updated in 2005 and 2016, Hope in the Dark provides modern examples of gains on race, class, environment, and queer rights. That said, this is not a feel-good book. It does not sugarcoat, for instance, the fact that we are headed toward ecological disaster. And if you look up the latest figures on the gender wage gap, you’ll find that they’ve hardly budged from those cited by Solnit years ago. Still, her deft logic and kooky aphorisms (“Don’t mistake a lightbulb for the moon, and don’t believe that the moon is useless unless we land on it”) have convinced me that to give up hope is to surrender the future. Fighting for progress can be exhausting and revelatory, full of both pain and pleasure. Solnit insists that doing so is never a waste.

[Read: Trump won. Now what?]

Women Talking, by Miriam Toews

The inspired-by-true-events premise of Toews’s seventh novel is literally the stuff of nightmares. In a remote Mennonite colony, women who have suffered mysterious attacks in the night learn that they’ve been drugged and raped by several men from their community. One woman is pregnant with her rapist’s child; another’s 3-year-old has a sexually transmitted infection. The novel takes place in the aftermath of the discovery, just after the men have been temporarily jailed. They are set to be bailed out in two days, and the colony’s bishop demands that the victims forgive them—or else face excommunication and be denied a spot in heaven. The women meet in secret to decide what to do: Comply? Fight back? Leave for an outside world they’ve never experienced? Even against this harrowing backdrop, Toews’s signature humor and eye for small moments of grace make Women Talking an enjoyable and healing read. The women’s discussions are both philosophical (they cannot read, so how can they trust that the Bible requires them to forgive the men?) and practical (if they leave, do they bring their male children?). Any direction they choose will lead to a kind of wilderness: “When we have liberated ourselves,” one woman says in a particularly stirring moment, “we will have to ask ourselves who we are.”

Good Talk, by Mira Jacob

Jacob’s graphic-memoir-in-conversations took major guts to write. It begins like this: The author’s white in-laws throw their support behind Trump’s 2016 presidential campaign, and her otherwise loving family toes the edge of collapse. Good Talk is a funny and painful book-length answer to questions from Jacob’s 6-year-old son, who is half Jewish and half Indian, about race, family, and identity. Jacob, who was raised in the United States by parents who emigrated from India, gorgeously illustrates her formative experiences, touching on respectability politics, colorism within the Indian community, her bisexuality, and her place in America. She refuses to caricaturize the book’s less savory characters—for example, a rich white woman who hires Jacob to ghostwrite her family’s biography and ends up questioning her integrity and oversharing the grisly details of her 2-year-old’s death from cancer. Jacob’s ability to so humanely render the people who cause her grief is powerful. My daughter is too young to ask questions, but one day, when she begins inquiring about the world she’s inheriting, I can tell her, as Jacob told her son, “If you still have hope, my love, then so do I.”

[Read: Hope and the historian]

The Twenty-Ninth Year, by Hala Alyan

Startling, sexy, and chaotic, The Twenty-Ninth Year is a collection of poems narrated by a woman on the verge—of a lot of things. She’s standing at the edge of maturity, of belonging as a Palestinian American, of recovery from anorexia and alcoholism. It’s a tender and violent place, evoked with images that catch in the throat. The first poem, “Truth,” takes the form of a litany of confessions: “I broke / into the bodies of men like a cartoon burglar”; “I’ve seen women eat cotton balls so they wouldn’t eat bread.” That Alyan is a clinical psychologist makes sense—her poems have a clarity that can’t be faked. Dark humor softens the blow of lines such as “I starved myself to starve my mother” and “Define in, I say when anyone asks if I’ve ever been in a war.” She reckons with the loneliness of living in exile and the danger of romanticizing the youthful conviction that there is something incurably wrong with you. A shallow read of the collection might be: I burned my life down so you don’t have to. But I return to the last line of the book: “Marry or burn; either way, you’re transfiguring.” There is always something to set aflame; more optimistically, there is always something left to salvage. The Twenty-Ninth Year is, in the end, a monument to endurance.

Riot Baby, by Tochi Onyebuchi

If you’re sick of books described as “healing” or “hopeful,” look no further than Riot Baby. Onyebuchi’s thrilling 2020 novella asks just how far sci-fi dystopias are from real life. Kev, a Black man born during the Rodney King riots in Los Angeles, California, spends much of his 20s in prison after a botched armed robbery. His sister, Ella, has more supernatural problems: She sees the past and the future and, when fury takes over, can raze cities to the ground—yet she could not protect her brother from the violence of incarceration. When Kev is paroled and a new form of policing via implantable chips and pharmaceutical infusions brings “safety” to the streets of Watts, Ella understands that the subjugation of her community is not a symptom of a broken system; rather, it is evidence of one “working just as designed,” as Onyebuchi put it in an interview. Ella must make a wrenching choice: fight for a defanged kind of freedom within such a system or usher in a new world order no matter the cost. In real life, too often, you cannot control your circumstances, only your actions. But you may find relief in reading a book that reaches a different conclusion.

[Read: When national turmoil becomes personal anxiety]

Let the Record Show: A Political History of ACT UP New York, 1987–1993, by Sarah Schulman

This 700-plus-page history of the AIDS Coalition to Unleash Power’s New York chapter is, I promise you, a page-turner. Schulman and the filmmaker Jim Hubbard, who were both in ACT UP New York, interviewed 188 members over the course of 17 years about the organization’s work on behalf of those living with HIV/AIDS—“a despised group of people, with no rights, facing a terminal disease for which there were no treatments,” Schulman writes. Part memoir and part oral history, Let the Record Show is a master class on the utility of anger and a historical corrective to chronicles that depict straight white men as the main heroes of the AIDS crisis. In reality, a diverse coalition of activists helped transform HIV into a highly manageable condition. “People who are desperate are much more effective than people who have time to waste,” Schulman argues. ACT UP was known for its brash public actions, and Schulman covers not just what the group accomplished but also how it did it, with electrifying detail. There can be no balm for the fact that many ACT UP members did not survive long enough to be interviewed. There is only awe at the way a group of people “unable to sit out a historic cataclysm” were determined to “force our country to change against its will,” and did.

The Anti-Immigration Measure That Trump Is Ignoring

The Atlantic

www.theatlantic.com › science › archive › 2024 › 11 › migration-climate-trump › 680696

In Mexico, the conditions that have contributed to the largest sustained movement of humans across any border in the world will get only more common. This spring, at the start of the corn-growing season, 76 percent of Mexico was in drought, and the country was sweltering under a deadly heat dome. Finally, after too many months, summer rains started to refill reservoirs. But years and droughts like this promise to become more intense: Mexico is slated to warm 1 to 3 degrees Celsius by 2060.

When drought strikes rural corn farmers in Mexico during the growing season, they are more likely to attempt to immigrate to the United States the following year out of economic desperation, according to a study released this month in the journal PNAS. This is just the latest example of a signal in migration data that keeps getting clearer: Climate change is pushing people to cross borders, and especially the southern border of the United States. Many live on the edge of financial stability; if one of their few options to support themselves is jeopardized, they might not recover. “And climate extremes are taking away whatever option there is there,” one of the study’s co-authors, Filiz Garip, a professor of sociology and public affairs at Princeton University, told me.

Donald Trump and his incoming administration have said that limiting immigration into the United States is a priority; the president-elect intends to both close the southern border and deploy the military in order to carry out mass deportations. He is also poised to ignore the climate altogether, and likely hasten the pace of change with policies that increase oil and gas drilling. That combination is “sort of like turning the heat up on a boiling pot and then forcing the lid shut,” Ama Francis, a lawyer and the climate director of the International Refugee Assistance Project (IRAP), told me. Drought and other climate disasters will help propel more people north; U.S. immigration policies will attempt to block them, but migrants won’t stop coming. Part of the argument for dealing with climate change, and doing so in partnership with the rest of the world, is that it will mitigate these sorts of pressures before they become even more dramatic conflicts. The next administration could be setting the country up for the opposite.

Climate isn’t usually the only factor that drives people to move, but it can be a tipping point that clinches their decision. Like many places in the world, Mexico is becoming a harder place to live because of both drought and extreme rainfall, which leads to flooding. These are particular challenges for rural farmers whose crop depends on the seasons progressing as they have for hundreds of years. More may make the desperate choice to leave. And more who have left may stay for longer in the United States. Garip’s study found that climate extremes will delay migrants from returning to their communities. “I was really taken aback by how strong the return results were,” she said. “These weather extremes continue to shape, it seems, how people think about whether to remain a migrant or whether to go back to their communities.”

Climate factors are not what many immigrants first cite as a reason for leaving their home. Violence and racial or political persecution will often come up before drought, for example. But start talking through the deeper roots, and in many cases, “climate-related factors do come up,” Alexander de Sherbinin, an expert on climate and human migration at Columbia University, told me. Francis’s organization, IRAP, which gives migrants legal support, recently co-published a report based on interviews with more than 3,000 clients, nearly half of whom had experienced a climate disaster in their home country before leaving. The most common of these was extreme rainfall, followed closely by extreme heat.

Even when demographers control for other characteristics in a person’s life, climate change still emerges as a statistically significant factor of migration, says Lori Hunter, the director of the Institute of Behavioral Science at the University of Colorado at Boulder, who has studied migration data for decades. The pattern is clear, Hunter told me: “If we disinvest from the climate, the pressure to migrate will intensify.”

Conversely, a certain subset of the potential immigrant population, if their climate desperation could be alleviated, may not choose to come to the United States. In the long term, dramatically lowering the U.S.’s emissions would help limit climate stresses, but the warming the world has already experienced is driving weather extremes right now. Adapting to new climatic normals is now necessary. Migration is one way of adapting. But people could, with assistance, adapt in place. Among the corn farmers Garip and her colleagues studied, those who had access to some form of irrigation infrastructure, such as a reservoir, were less likely to leave, even when faced with drought conditions. It was mostly rural, smallholder farmers entirely dependent on rainfall who decided to make the perilous trek north. With investment for projects to install irrigation in those communities, “these decisions could really be different,” Garip said. “Unless we do something, then we’re just pushing more people into this dangerous journey.”

Indeed, the biggest topic at the global COP29 climate negotiations, under way in Baku, Azerbaijan, is the dollar amount that developed countries, responsible for the majority of historical emissions, will transfer to developing countries, which are bearing the brunt of the climate crisis and require at least $1 trillion of outside funding per year to build more renewable energy and respond to climate-driven disasters. Many at COP assume that the U.S. won’t contribute to those funds at all, and the meeting, now at its halfway point, is by all accounts at a deadlock, with little leadership from wealthy countries materializing. The Biden administration had plans to fund $3 billion worth of climate adaptation internationally each year, with a special focus on water security—and explicitly framed that as a tool to “address key drivers of migration.” Those plans are unlikely to continue into the next Trump presidency.

Climate finance is a nebulous category, and a lack of transparency about how the funds get spent can undermine the process. But other research has found that remittances—money that migrants send home—tend to be spent on things that improve climate resilience, such as air-conditioning. To Hunter, that remittance data suggest that international climate finance could be spent in ways that would help people adapt to climate change where they live, and remove one of the factors that force them to leave. If a motivated government made a real effort to supply that funding in the first place, perhaps those communities would not feel that they had to send a family member north. It wouldn’t stop migration altogether, but it could help reduce the pressures the incoming Trump administration is so eager to address.

She Was an Education Superstar. Then She Got Blamed for America’s Reading Crisis.

The Atlantic

www.theatlantic.com › magazine › archive › 2024 › 12 › lucy-calkins-child-literacy-teaching-methodology › 680394

This story seems to be about:

Photographs by Jeff Brown

Until a couple of years ago, Lucy Calkins was, to many American teachers and parents, a minor deity. Thousands of U.S. schools used her curriculum, called Units of Study, to teach children to read and write. Two decades ago, her guiding principles—that children learn best when they love reading, and that teachers should try to inspire that love—became a centerpiece of the curriculum in New York City’s public schools. Her approach spread through an institute she founded at Columbia University’s Teachers College, and traveled further still via teaching materials from her publisher. Many teachers don’t refer to Units of Study by name. They simply say they are “teaching Lucy.”

But now, at the age of 72, Calkins faces the destruction of everything she has worked for. A 2020 report by a nonprofit described Units of Study as “beautifully crafted” but “unlikely to lead to literacy success for all of America’s public schoolchildren.” The criticism became impossible to ignore two years later, when the American Public Media podcast Sold a Story: How Teaching Kids to Read Went So Wrong accused Calkins of being one of the reasons so many American children struggle to read. (The National Assessment of Educational Progress—a test administered by the Department of Education—found in 2022 that roughly one-third of fourth and eighth graders are unable to read at the “basic” level for their age.)

In Sold a Story, the reporter Emily Hanford argued that teachers had fallen for a single, unscientific idea—and that its persistence was holding back American literacy. The idea was that “beginning readers don’t have to sound out words.” That meant teachers were no longer encouraging early learners to use phonics to decode a new word—to say cuh-ah-tuh for “cat,” and so on. Instead, children were expected to figure out the word from the first letter, context clues, or nearby illustrations. But this “cueing” system was not working for large numbers of children, leaving them floundering and frustrated. The result was a reading crisis in America.

The podcast said that “a company and four of its top authors” had sold this “wrong idea” to teachers and politicians. The company was the educational publisher Heinemann, and the authors included the New Zealander Marie Clay, the American duo Irene Fountas and Gay Su Pinnell, and Calkins. The podcast devoted an entire episode, “The Superstar,” to Calkins. In it, Hanford wondered if Calkins was wedded to a “romantic” notion of literacy, where children would fall in love with books and would then somehow, magically, learn to read. Calkins could not see that her system failed poorer children, Hanford argued, because she was “influenced by privilege”; she had written, for instance, that children might learn about the alphabet by picking out letters from their surroundings, such as “the monogram letters on their bath towels.”

In Hanford’s view, it was no surprise if Calkins’s method worked fine for wealthier kids, many of whom arrive at school already starting to read. If they struggled, they could always turn to private tutors, who might give the phonics lessons that their schools were neglecting to provide. But kids without access to private tutors needed to be drilled in phonics, Hanford argued. She backed up her claims by referencing neurological research into how children learn to read—gesturing to a body of evidence known as “the science of reading.” That research demonstrated the importance of regular, explicit phonics instruction, she said, and ran contrary to how American reading teachers were being trained.

Since the podcast aired, “teaching Lucy” has fallen out of fashion. Calkins’s critics say that her refusal to acknowledge the importance of phonics has tainted not just Units of Study—a reading and writing program that stretches up to eighth grade—but her entire educational philosophy, known as “balanced literacy.” Forty states and the District of Columbia have passed laws or implemented policies promoting the science of reading in the past decade, according to Education Week, and publishers are racing to adjust their offerings to embrace that philosophy.

Somehow, the wider debate over how to teach reading has become a referendum on Calkins herself. In September 2023, Teachers College announced that it would dissolve the reading-and-writing-education center that she had founded there. Anti-Lucy sentiment has proliferated, particularly in the city that once championed her methods: Last year, David Banks, then the chancellor of New York City public schools, likened educators who used balanced literacy to lemmings: “We all march right off the side of the mountain,” he said. The New Yorker has described Calkins’s approach as “literacy by vibes,” and in an editorial, the New York Post described her initiative as “a disaster” that had been “imposed on generations of American children.” The headline declared that it had “Ruined Countless Lives.” When the celebrated Harvard cognitive psychologist Steven Pinker shared an article about Calkins on X, he bemoaned “the scandal of ed schools that promote reading quackery.” Queen Lucy has been dethroned.

“I mean, I can say it—it was a little bit like 9/11,” Calkins told me when we spoke at her home this summer. On that day in 2001, she had been driving into New York City, and “literally, I was on the West Side Highway and I saw the plane crash into the tower. Your mind can’t even comprehend what’s happening.” Two decades later, the suggestion that she had harmed children’s learning felt like the same kind of gut punch.

Calkins now concedes that some of the problems identified in Sold a Story were real. But she says that she had followed the research, and was trying to rectify issues even before the podcast debuted: She released her first dedicated phonics units in 2018, and later published a series of “decodable books”—simplified stories that students can easily sound out. Still, she has not managed to satisfy her critics, and on the third day we spent together, she admitted to feeling despondent. “What surprises me is that I feel as if I’ve done it all,” she told me. (Heinemann, Calkins’s publisher, has claimed that the Sold a Story podcast “radically oversimplifies and misrepresents complex literacy issues.”)

The backlash against Calkins strikes some onlookers, even those who are not paid-up Lucy partisans, as unfair. “She wouldn’t have been my choice for the picture on the ‘wanted’ poster,” James Cunningham, a professor emeritus of literacy studies at the University of North Carolina at Chapel Hill, told me. Indeed, over the course of several days spent with Calkins, and many more hours talking with people on all sides of this debate, I came to see her downfall as part of a larger story about the competing currents in American education and the universal desire for an easy, off-the-shelf solution to the country’s reading problems.

The question now is whether Calkins is so much a part of the problem that she cannot be part of the solution. “I’m going to figure this out,” she remembered thinking. “And I’m going to clarify it or I’m going to write some more or speak or do something or, or—fix it.” But can she? Can anyone?

On the last day of the school year in Oceanside, a well-to-do town on Long Island, everyone was just delighted to see Lucy Calkins. The young Yale-educated principal of Fulton Avenue School 8, Frank Zangari, greeted her warmly, and at the end of one lesson, a teacher asked for a selfie.

The lessons I saw stressed the importance of self-expression and empathy with other viewpoints; a group of sixth graders told me about the books they had read that year, which explored being poor in India and growing up Black in 1960s America. In every class, I watched Calkins speak to children with a mixture of intense attention and straightforward challenge; she got down on the floor with a group learning about orcas and frogs and peppered them with questions about how animals breathe. “Could you talk a minute about the writer’s craft?” she asked the sixth graders studying poetry. “Be more specific. Give examples,” she told a fourth grader struggling to write a memoir.

With her slim frame, brown bob, and no-nonsense affect, she reminded me of Nancy Pelosi. “I can’t retire; I don’t have any hobbies,” I overheard her saying to someone later.

School 8 showed the strengths of Calkins’s approach—which is presumably why she had suggested we visit it together. But it also hinted at the downsides. For generations in American public education, there has been a push and pull between two broad camps—one in which teachers are encouraged to directly impart skills and information, and a more progressive one in which children are thought to learn best through firsthand experience. When it comes to reading, the latter approach dominates universities’ education programs and resonates with many teachers; helping children see themselves as readers and writers feels more emotionally satisfying than drilling them on diphthongs and trigraphs.

This tension between the traditionalists and the progressives runs through decades of wrangling over standardized tests and through most of the major curricular controversies in recent memory. Longtime educators tick off the various flash points like Civil War battlefields: outcome-based education, No Child Left Behind, the Common Core. Every time, the pendulum went one way and then the other. “I started teaching elementary school in 1964,” says P. David Pearson, a former dean at the Berkeley School of Education, in California. “And then I went to grad school in, like, ’67, and there’s been a back-to-the-basics swing about every 10 years in the U.S., consistently.”

The progressives’ primary insight is that lessons focused on repetitive instruction and simplified text extracts can be boring for students and teachers alike, and that many children respond more enthusiastically to discovering their own interests. “We’re talking about an approach that treats kids as competent, intellectual meaning makers, versus kids who just need to learn the code,” Maren Aukerman, a professor at the University of Calgary, told me. But opponents see that approach as nebulous and undirected.

My time at School 8 was clearly intended to demonstrate that Units of Study is not hippie nonsense, but a rigorous curriculum that can succeed with the right teachers. “There’s no question in my mind that the philosophy works, but in order to implement it, it takes a lot of work,” Phyllis Harrington, the district superintendent, told me.

School 8 is a happy school with great results. However, while the school uses Calkins’s writing units for all grades, it uses her reading units only from the third grade on. For first and second grades, the school uses Fundations, which is marketed as “a proven approach to Structured Literacy that is aligned with the science of reading.” In other words, it’s a phonics program.

Calkins’s upbringing was financially comfortable but psychologically tough. Both of her parents were doctors, and her father eventually chaired the department of medicine at the University at Buffalo. Calkins’s mother was “the most important, wonderful person in my life, but really brutal,” she told me. If a bed wasn’t made, her mother ripped off the sheets. If a coat wasn’t hung up, her mother dropped it into the basement. When the young Lucy bit her fingernails, her mother tied dancing gloves onto her hands. When she scratched the mosquito bites on her legs, her mother made her wear thick pantyhose at the height of summer.

The nine Calkins children raised sheep and chickens themselves. Her memories of childhood are of horseback riding in the cold, endless hand-me-downs, and little tolerance for bad behavior.

That is why, Calkins told me, “nothing that Emily Hanford has said grates on me more than the damn monogrammed towels.” But she knows that the charge of being privileged and out of touch has stuck. Her friends had warned her about letting me into her home in Dobbs Ferry, a pretty suburb of New York, and I could see why. Her house is idyllic—at the end of a long private drive, shaded by old trees, with a grand piano in the hallway and a Maine-coon cat patrolling the wooden floors. Calkins has profited handsomely from textbook sales and training fees, and in the eyes of some people, that is suspicious. (“Money is the last thing I ever think about,” she told me.)

She became interested in reading and writing because she babysat for the children of the literacy pioneer Donald Graves, whose philosophy can be summarized by one of his most widely cited phrases: “Children want to write.” Even at a young age, she believed in exhaustively prepared fun. “I would plan a bagful of things I would bring over there; I was the best babysitter you could ever have,” she said. “We would do crafts projects, and drama, you know, and I would keep the kids busy all day.”

When Calkins was 14, Graves sent her to be a counselor at a summer camp in rural Maine. She remembers two kids in particular, Sophie and Charlie. Sophie was “so tough and surly, and a kind of overweight, insecure, tough kid,” but she opened up when Calkins took her horseback riding and then asked her to write about it. Charlie loved airplanes, and so she asked him to write about those. The experience cemented her lifelong belief that children should read and write as a form of self-expression.

After graduating from Williams College in 1973, she enrolled in a program in Connecticut that trained teachers to work in disadvantaged districts. She read everything about teaching methods she could find, and traveled to England, where a progressive education revolution was in full swing.

Calkins returned to America determined to spread this empowering philosophy. She earned a doctorate at NYU, and, in 1986, published a book called The Art of Teaching Writing. Later, she expanded her purview to reading instruction.

At the time, the zeitgeist favored an approach known as “whole language.” This advocated independent reading of full books and suggested that children should identify words from context clues rather than arduously sounding them out. Progressives loved it, because it emphasized playfulness and agency. But in practice, whole language had obvious flaws: Some children do appear to pick up reading easily, but many benefit from focused, direct instruction.

This approach influenced Calkins as she developed her teaching philosophy. “Lucy Calkins sides, in most particulars, with the proponents of ‘whole language,’ ” The New York Times reported in 1997. Her heavyweight 2001 book, The Art of Teaching Reading, has only a single chapter on phonics in primary grades; it does note, however, that “researchers emphasize how important it is for children to develop phonemic awareness in kindergarten.”

The author Natalie Wexler has described Calkins’s resulting approach, balanced literacy, as an attempt to create a “peace treaty” in the reading wars: Phonics, yes, if you must, but also writing workshops and independent reading with commercial children’s books, rather than the stuffier grade-level decodable texts and approved extracts. (Defenders of the former method argue that using full books is more cost-efficient, because they can be bought cheaply and used by multiple students.) “If we make our children believe that reading has more to do with matching letters and sounds than with developing relationships with characters like Babar, Madeline, Charlotte, and Ramona,” Calkins wrote, “we do more harm than good.”

Sentences like that are why critics saw balanced literacy as a branding exercise designed to rehabilitate old methods. “It was a strategic rebadging of whole language,” Pamela Snow, a cognitive-psychology professor at La Trobe University, in Australia, told me. Even many of Calkins’s defenders concede that she was too slow to embrace phonics as the evidence for its effectiveness grew. “I think she should have reacted earlier,” Pearson, the former Berkeley dean, told me, but he added: “Once she changed, they were still beating her for what she did eight years ago, not what she was doing last month.”

For the first decades of her career, Calkins was an influential thinker among progressive educators, writing books for teachers. In 2003, though, Joel Klein, then the chancellor of the New York City public schools, suddenly mandated her workshop approach in virtually all of the city’s elementary schools, alongside a separate, much smaller, phonics program. An article in the Times suggested that some saw Klein as “an unwitting captive of the city’s liberal consensus,” but Klein brushed aside the criticisms of balanced literacy. “I don’t believe curriculums are the key to education,” he said. “I believe teachers are.” Now everybody in the city’s public schools would be “teaching Lucy.”

As other districts followed New York’s lead, Units of Study became one of the most popular curricula in the United States. This led, inevitably, to backlash. A philosophy had become a product—an extremely popular and financially successful one. “Once upon a time there was a thoughtful educator who raised some interesting questions about how children were traditionally taught to read and write, and proposed some innovative changes,” the author Barbara Feinberg wrote in 2007. “But as she became famous, critical debate largely ceased: her word became law. Over time, some of her methods became dogmatic and extreme, yet her influence continued to grow.”

You wouldn’t know it from listening to her fiercest detractors, but Calkins has, in fact, continuously updated Units of Study. Unlike Irene Fountas and Gay Su Pinnell, who have stayed quiet during the latest furor and quietly reissued their curriculum with more emphasis on phonics last year, Calkins has even taken on her critics directly. In 2019—the year after she added the dedicated phonics texts to Units of Study—she published an eight-page document called “No One Gets to Own the Term ‘The Science of Reading,’ ” which referred dismissively to “phonics-centric people” and “the new hype about phonics.” This tone drove her opponents mad: Now that Calkins had been forced to adapt, she wanted to decide what the science of reading was?

“Her document is not about the science that I know; it is about Lucy Calkins,” wrote the cognitive neuroscientist Mark Seidenberg, one of the critics interviewed in Sold a Story. “The purpose of the document is to protect her brand, her market share, and her standing among her many followers.”

Talking with Calkins herself, it was hard to nail down to what extent she felt that the criticisms of her earlier work were justified. When I asked her how she was thinking about phonics in the 2000s, she told me: “Every school has a phonics program. And I would always talk about the phonics programs.” She added that she brought phonics specialists to Columbia’s Teachers College several times a year to help train aspiring educators. (James Cunningham, at UNC Chapel Hill, backed this up, telling me, “She was certainly not wearing a sandwich billboard around: DON’T TEACH PHONICS.”)

But still, I asked Calkins, would it be fair to say that phonics wasn’t your bag?

“I felt like phonics was something that you have the phonics experts teach.”

So where does this characterization of you being hostile toward phonics come from?

“Hopefully, you understand I’m not stupid. You would have to be stupid to not teach a 5-year-old phonics.”

But some people didn’t, did they? They were heavily into context and cueing.

“I’ve never heard of a kindergarten teacher who doesn’t teach phonics,” Calkins replied.

Because this is America, the reading debate has become a culture war. When Sold a Story came along in 2022, it resonated with a variety of audiences, including center-left education reformers and parents of children with learning disabilities. But it also galvanized political conservatives. Calkins’s Units of Study was already under attack from the right: In 2021, an article in the Manhattan Institute’s City Journal titled “Units of Indoctrination” had criticized the curriculum, alleging that the way it teaches students to analyze texts “amounts to little more than radical proselytization through literature.”

The podcast was released at an anxious time for American education. During the coronavirus pandemic, many schools—particularly in blue states—were closed for months at a time. Masking in classrooms made it harder for children to lip-read what their teachers were saying. Test scores fell, and have only recently begun to recover.

“Parents had, for a period of time, a front-row seat based on Zoom school,” Annie Ward, a recently retired assistant superintendent in Mamaroneck, New York, told me. She wondered if that fueled a desire for a “back to basics” approach. “If I’m a parent, I want to know the teacher is teaching and my kid is sitting there soaking it up, and I don’t want this loosey-goosey” stuff.

Disgruntled parents quickly gathered online. Moms for Liberty, a right-wing group that started out by opposing school closures and mask mandates, began lobbying state legislators to change school curricula as well. The reading wars began to merge with other controversies, such as how hard schools should push diversity-and-inclusion programs. (The Moms for Liberty website recommends Sold a Story on its resources page.) “We’re failing kids everyday, and Moms for Liberty is calling it out,” a co-founder, Tiffany Justice, told Education Week in October of last year. “The idea that there’s more emphasis placed on diversity in the classroom, rather than teaching kids to read, is alarming at best. That’s criminal.”

Ward’s district was not “teaching Lucy,” but using its own bespoke balanced-literacy curriculum. In the aftermath of the pandemic, Ward told me, the district had several “contentious” meetings, including one in January 2023 where “we had ringers”—attendees who were not parents or community members, but instead seemed to be activists from outside the district. “None of us in the room recognized these people.” That had never happened before.

I had met Ward at a dinner organized by Calkins at her home, which is also the headquarters of Mossflower—the successor to the center that Calkins used to lead at Teachers College. The evening demonstrated that Calkins still has star power. On short notice, she had managed to assemble half a dozen superintendents, assistant superintendents, and principals from New York districts.

“Any kind of disruption like this has you think very carefully about what you’re doing,” Edgar McIntosh, an assistant superintendent in Scarsdale, told me. But he, like several others, was frustrated by the debate. During his time as an elementary-school teacher, he had discovered that some children could decode words—the basic skill developed by phonics—but struggled with their meaning. He worried that parents’ clamor for more phonics might come at the expense of teachers’ attention to fluency and comprehension. Raymond Sanchez, the superintendent of Tarrytown’s school district, said principals should be able to explain how they were adding more phonics or decodable texts to existing programs, rather than having “to throw everything out and find a series that has a sticker that says ‘science of reading’ on it.”

This, to me, is the key to the anti-Lucy puzzle. Hanford’s reporting was thorough and necessary, but its conclusion—that whole language or balanced literacy would be replaced by a shifting, research-based movement—is hard to reconcile with how American education actually works. The science of reading started as a neutral description of a set of principles, but it has now become a brand name, another off-the-shelf solution to America’s educational problems. The answer to those problems might not be to swap out one commercial curriculum package for another—but that’s what the system is set up to enable.

Gail Dahling-Hench, the assistant superintendent in Madison, Connecticut, has experienced this pressure firsthand. Her district’s schools don’t “teach Lucy” but instead follow a bespoke local curriculum that, she says, uses classroom elements associated with balanced literacy, such as the workshop model of students studying together in small groups, while also emphasizing phonics. That didn’t stop them from running afoul of the new science-of-reading laws.

In 2021, Connecticut passed a “Right to Read” law mandating that schools choose a K–3 curriculum from an approved list of options that are considered compliant with the science of reading. Afterward, Dahling-Hench’s district was denied a waiver to keep using its own curriculum. (Eighty-five districts and charter schools in Connecticut applied for a waiver, but only 17 were successful.) “I think they got wrapped around the axle of thinking that programs deliver instruction, and not teachers,” she told me.

Dahling-Hench said the state gave her no useful explanation for its decision—nor has it outlined the penalties for noncompliance. She has decided to stick with the bespoke curriculum, because she thinks it’s working. According to test scores released a few days after our conversation, her district is among the best-performing in the state.

Keeping the current curriculum also avoids the cost of preparing teachers and administrators to use a new one—a transition that would be expensive even for a tiny district like hers, with just five schools. “It can look like $150,000 to $800,000 depending on which program you’re looking at, but that’s a onetime cost,” Dahling-Hench said. Then you need to factor in annual costs, such as new workbooks.

You can’t understand this controversy without appreciating the sums involved. Refreshing a curriculum can cost a state millions of dollars. People on both sides will therefore suggest that their opponents are motivated by money—either saving their favored curriculum to keep the profits flowing, or getting rich through selling school boards an entirely new one. Talking with teachers and researchers, I heard widespread frustration with America’s commercial approach to literacy education. Politicians and bureaucrats tend to love the idea of a packaged solution—Buy this and make all your problems go away!—but the perfect curriculum does not exist.

“If you gave me any curriculum, I could find ways to improve it,” Aukerman, at the University of Calgary, told me. She thinks that when a teaching method falls out of fashion, its champions are often personally vilified, regardless of their good faith or expertise. In the case of Lucy Calkins and balanced literacy, Aukerman said, “If it weren’t her, it would be someone else.”

Jeff Brown for The Atlantic

One obvious question about the science of reading is, well … what is it? The evidence for some kind of explicit phonics instruction is compelling, and states such as Mississippi, which has adopted early screening to identify children who struggle to read—and which holds back third graders if necessary—appear to be improving their test scores. Beyond that, though, things get messy.

Dig into this subject, and you can find frontline teachers and credentialed professors who contest every part of the consensus. And I mean every part: Some academics don’t even think there’s a reading crisis at all.

American schools might be ditching Units of Study, but balanced literacy still has its defenders. A 2022 analysis in England, which mandates phonics, found that systematic reviews “do not support a synthetic phonics orientation to the teaching of reading; they suggest that a balanced-instruction approach is most likely to be successful.”

The data on the effects of specific methods can be conflicting and confusing, which is not unusual for education studies, or psychological research more generally. I feel sorry for any well-intentioned superintendent or state legislator trying to make sense of it all. One of the classrooms at Oceanside School 8 had a wall display devoted to “growth mindset,” a fashionable intervention that encourages children to believe that instead of their intelligence and ability being fixed, they can learn and evolve. Hoping to improve test scores, many schools have spent thousands of dollars each implementing “growth mindset” lessons, which proponents once argued should be a “national education priority.” (Some proponents also hoped, earnestly, that the approach could help bring peace to the Middle East.) But in the two decades since growth mindset first became ubiquitous, the lofty claims made about its promise have come down to earth.

Keeping up with all of this is more than any teacher—more than any school board, even—can reasonably be expected to do. After I got in touch with her, Emily Hanford sent me seven emails with links to studies and background reading; I left Calkins’s house loaded down with units of her curricula for younger students. More followed in the mail.

Even the most modest pronouncements about what’s happening in American schools are difficult to verify, because of the sheer number of districts, teachers, and pupils involved. In Sold a Story, Hanford suggested that some schools were succeeding with Units of Study only because parents hired personal tutors for their children. But corroborating this with data is impossible. “I haven’t figured out a way to quantify it, except in a very strong anecdotal way,” Hanford told me.

Some teachers love “teaching Lucy,” and others hate it. Is one group delusional? And if so, which one? Jenna and Christina, who have both taught kindergarten in New York using Units of Study, told me that the curriculum was too invested in the idea of children as “readers” and “writers” without giving them the basic skills needed to read and write. (They asked to be identified only by their first names in case of professional reprisals.) “It’s a piece of shit,” Christina said. She added: “We’re expecting them to apply skills that we haven’t taught them and that they aren’t coming to school with. I’ve been trying to express that there’s a problem and I get called negative.” Jenna had resorted to a covert strategy, secretly teaching phonics for up to 90 minutes a day instead of the brief lessons she was instructed to provide.

But for every Jenna or Christina, there’s a Latasha Holt. After a decade as a third- and fourth-grade teacher in Arkansas, Holt is now an associate professor of elementary literacy at the University of Louisiana at Lafayette, where she has watched from the sidelines as the tide turned against Calkins. “The dismantling of this thing, it got to me, because I had taught under Units of Study,” she told me. “I’ve used it, and I knew how good it was. I had lived it; I’ve seen it work; I knew it was good for kids.”

Aubrey Kinat is a third-grade teacher in Texas who recently left her position at a public school because it decided to drop Units of Study. (The school now uses another curriculum, which was deemed to align better with the science of reading.) Suddenly, she was pushed away from full novels and toward approved excerpts, and her lessons became much more heavily scripted. “I felt like I was talking so much,” she told me. “It took the joy out of it.”

For many school boards facing newly politicized parents who came out of the pandemic with strong opinions, ditching Lucy has had the happy side effect of giving adults much more control over what children read. Calkins and some of her dinner guests had suggested that this might be the true reason for the animus around independent reading. “I do start to wonder if this really is about wanting to move everybody towards textbooks,” Calkins said.

Eighteen months after her series launched, Hanford returned in April 2024 with two follow-up episodes of Sold a Story, which took a less polemical tone. Unsurprisingly so: Calkins had lost, and she had won.

The science of reading is the new consensus in education, and its advocates are the new establishment. It is now on the hook for the curriculum changes that it prompted—and for America’s reading performance more generally. That is an uncomfortable position for those who care more about research than about winning political fights.

Some of the neuroscience underpinning Sold a Story was provided by Seidenberg, a professor emeritus at the University of Wisconsin at Madison. (He did not respond to an interview request.) Since the series aired, he has welcomed the move away from Units of Study, but he has also warned that “none of the other major commercial curricula that are currently available were based on the relevant science from the ground up.”

Because the usefulness of phonics is one of the few science-of-reading conclusions that is immediately comprehensible to laypeople, “phonics” has come to stand in for the whole philosophy. In a blog post last year, Seidenberg lamented that, on a recent Zoom call, a teacher had asked if they needed to keep teaching phonemic awareness once children were good readers. (The answer is no: Sounding out letters is what you do until the process becomes automatic.) Seidenberg now worried that the science of reading is “at risk of turning into a new pedagogical dogma.”

Hanford has also expressed ambivalence about the effects of Sold a Story. She compared the situation to the aftermath of No Child Left Behind, a George W. Bush–era federal education initiative that heavily promoted a literacy program called Reading First. “It became focused on products and programs,” Hanford told me, adding that the ethos turned into “get rid of whole language and buy something else.” However, she is glad that the importance of phonics—and the research backing it—is now more widely understood, because she thinks this can break the cycle of revolution and counterrevolution. She added that whenever she talks with lawmakers, she stresses the importance of continuing to listen to teachers.

What about her portrait of Calkins as rich, privileged, oblivious? Forget the monogrammed towels, I told Hanford; there is a more benign explanation for Calkins’s worldview: Everywhere she goes, she meets people, like the teachers and children in Oceanside, who are overjoyed to see her, and keen to tell her how much they love Units of Study.

But Hanford told me that she’d included the towels line because “the vast majority of teachers, especially elementary-school teachers, in America are white, middle-class women.” Many of these women, she thought, had enjoyed school themselves and didn’t intuitively know what it was like to struggle with learning to read and write.

Reporting this story, I was reminded again and again that education is both a mass phenomenon and a deeply personal one. People I spoke with would say things like Well, he’s never done any classroom research. She’s never been a teacher. They don’t understand things the way I do. The education professors would complain that the cognitive scientists didn’t understand the history of the reading wars, while the scientists would complain that the education professors didn’t understand the latest peer-reviewed research. Meanwhile, a teacher must command a class that includes students with dyslexia as well as those who find reading a breeze, and kids whose parents read to them every night alongside children who don’t speak English at home. At the same time, school boards and state legislators, faced with angry parents and a welter of conflicting testimony, must answer a simple question: Should we be “teaching Lucy,” or not?

No matter how painful the past few years have been, though, Calkins is determined to keep fighting for her legacy. At 72, she has both the energy to start over again at Mossflower and the pragmatism to have promised her estate to further the cause once she’s gone. She still has a “ferocious” drive, she told me, and a deep conviction in her methods, even as they evolve. She does not want “to pretend it’s a brand-new approach,” she said, “when in fact we’ve just been learning; we’re just incorporating more things that we’ve learned.”

But now that balanced literacy is as unfashionable as whole language, Calkins is trying to come up with a new name for her program. She thought she might try “comprehensive literacy”—or maybe “rebalancing literacy.” Whatever it takes for America to once again feel confident about “teaching Lucy.”

This article appears in the December 2024 print edition with the headline “Teaching Lucy.” When you buy a book using a link on this page, we receive a commission. Thank you for supporting The Atlantic.

‘We Never Dared to Think About the Cure’

The Atlantic

www.theatlantic.com › health › archive › 2024 › 11 › lupus-car-t-immune-reset-autoimmune-disease › 680521

Lupus, doctors like to say, affects no two patients the same. The disease causes the immune system to go rogue in a way that can strike virtually any organ in the body, but when and where is maddeningly elusive. One patient might have lesions on the face, likened to wolf bites by the 13th-century physician who gave lupus its name. Another patient might have kidney failure. Another, fluid around the lungs. What doctors can say to every patient, though, is that they will have lupus for the rest of their life. The origins of autoimmune diseases like it are often mysterious, and an immune system that sees the body it inhabits as an enemy will never completely relax. Lupus cannot be cured. No autoimmune disease can be cured.

Two years ago, however, a study came out of Germany that rocked all of these assumptions. Five patients with uncontrolled lupus went into complete remission after undergoing a repurposed cancer treatment called CAR-T-cell therapy, which largely wiped out their rogue immune cells. The first treated patient has had no symptoms for almost four years now. “We never dared to think about the cure for our disease,” says Anca Askanase, a rheumatologist at Columbia University’s medical center who specializes in lupus. But these stunning results—remission in every patient—have fueled a new wave of optimism. More than 40 people with lupus worldwide have now undergone CAR-T-cell therapy, and most have gone into drug-free remission. It is too early to declare any of these patients cured for life, but that now seems within the realm of possibility.

Beyond lupus, doctors hope CAR-T portends a bigger breakthrough against autoimmune diseases, whose prevalence has been on a troubling rise. CAR-T has already been used experimentally to treat patients with other autoimmune diseases, including multiple sclerosis, myositis, and myasthenia gravis. And the success of CAR-T has inspired researchers to borrow other—cheaper and simpler—strategies from cancer therapy to kill immune cells gone awry. Not all of these ideas will pan out, but if any do, the next few years could bring an inflection point in treating some of the most frustrating and intractable diseases of our modern era.

CAR-T-cell therapy was originally developed as a way to kill malignant cells in blood cancer. It could, scientists later reasoned, also be used to kill specific white blood cells, called B cells, that go haywire with certain autoimmune diseases. One group tried a CAR-T-like therapy against an autoimmune disease called pemphigus vulgaris, and another CAR-T against lupus. It worked—but these experiments were only in mice.

This was the sum total of available scientific evidence when a 20-year-old woman came to her doctors in Erlangen, Germany, asking to try anything for her severe and uncontrolled lupus. None of the long-term medications typically used to manage lupus were working. Her kidneys, heart, and lungs were all failing, and she could walk only 30 feet by herself. CAR-T was risky, her doctor agreed, but lupus was killing her.

CAR-T-cell therapy could essentially turn her immune system against itself. First, doctors extracted from her blood a class of immune cells, called T cells, which they then engineered into chimeric antigen receptor T (CAR-T) cells that could recognize and destroy the B cells driving her lupus. CAR-T cells can cause dangerous and overwhelming inflammatory responses in cancer patients, and her doctors did worry that CAR-T could do the same for someone with autoimmune disease, whose immune system is already in overdrive. “We take the T cells out, activate them like crazy, and then shoot those massively overactivated T cells in an activated autoimmune disease. So if you think about it, that's kind of crazy to do that, right?” says Fabian Müller, a hematologist-oncologist at the University Hospital of Erlangen and one of the doctors on the German team that pioneered the treatment. But fortunately, the woman with lupus did not have any serious side effects, nor did any of the other patients the German group has since dosed. They are all living their everyday lives, free of lupus symptoms and medications. The woman who could walk a mere 30 feet now runs five times a week, Müller told me. She’s gone back to school and is considering studying for a master’s in immunology.

Müller and his colleagues believe that CAR-T-cell therapy works by wiping out enough B cells to trigger a “deep reset” of the immune system. CAR-T cells are dogged little assassins; they are able to find and destroy even the B cells hiding deep in the body’s tissues. A patient’s B-cell count eventually recovers, but the new ones no longer erroneously attack the body itself. Cancer patients are sometimes considered “cured” after five years of remission, and the first lupus patient to receive CAR-T is not so far off from that milestone. But the therapy cannot erase the genetic predisposition many patients have for the disease, says Donald Thomas, a rheumatologist in Maryland. Whether remission is actually durable enough to be a “cure” will take time to find out.

Still, these extraordinary results have set off a gold rush among biotech companies eager to solve autoimmune diseases. CAR-T start-ups founded to treat cancer are pivoting to target autoimmune diseases. And large pharmaceutical companies such as Bristol Myers Squibb, AstraZeneca, and Novartis are developing their own therapies. Columbia’s Askanase is now an investigator on five separate trials, all using CAR-T or a similar cellular therapy, and she hears from more companies all the time. There’s so much interest, she told me, “I don’t even know there are enough patients” to test new treatments. About 1.5 million Americans have lupus, but only a minority of them—those sick enough to justify experimental treatment but not so sick that they’ve suffered too much irreversible organ damage—are eligible for trials.

For now, CAR-T for lupus and other autoimmune diseases is pretty much only accessible in the U.S. through clinical trials—which, in effect, means it’s inaccessible to almost all lupus patients. Jonathan Greer, a rheumatologist in Florida, works in a seven-doctor practice that treats hundreds of people with lupus; not a single one has received CAR-T. He doesn’t know of a single center in Florida that is up and running to do these studies, so interested patients would have to travel out of state.

Even if it becomes FDA approved for autoimmune diseases, CAR-T is a long and expensive process. Because each patient’s own cells are reengineered, it cannot be easily scaled up. The cost of CAR-T for cancer runs about $500,000. Patients also need chemotherapy to kill existing T cells to make room for CAR-T, which adds risk, and in lupus, they usually need to taper off any medications keeping their disease in check, which can cause flare-ups. All these complications make the current iteration of CAR-T suitable only for lupus patients with severe disease, who have run out of other options.

The practical limitations of CAR-T have dogged the cancer field for a long time now, and researchers have already come up with ideas to get around it. A number of simpler strategies for killing B cells are now making their way from blood cancer to autoimmune disease. They include using donor T cells, a different type of immune cell called natural killer cells, or a molecule that binds a T cell to the B cell it’s meant to destroy. Those molecules, called bispecific T-cell engagers, or BiTEs, are “cheap, fast, uncomplicated,” Müller said, but they may not penetrate as deeply into the tissues where B cells reside. Nevertheless, in September, The New England Journal of Medicine published two successful case reports describing successful treatment in a handful of autoimmune diseases, including lupus, with a BiTE called teclistamab. Similar BiTES on the market could be repurposed for autoimmune disease too.

These simpler therapies may ultimately be “good enough,” Askanase said. And their ease of use could ultimately beat out custom CAR-T therapy, which is unlikely to reach all of the millions of people with lupus worldwide. It’s simply too expensive and too cumbersome, a problem that has held back other cutting-edge therapies that were approved to much initial fanfare. Even if CAR-T itself is never widely adopted for autoimmune diseases, it has opened the door to new ideas that could one day revolutionize their treatment.